Information Systems director at a large medical center

Assume you are a recently hired Information Systems director at a large medical center. You realize that there are a number of employees whose job duties would allow them to work from home. Because your boss has asked you for a space reduction proposal, there is need to implement a work-at-home program for employees
a) What steps should you take in developing a security program for the employees who will work from home?
b) Identify security threats that can occur during electronic transmission of data and how you could mitigate